Clindamycin versus Trimethoprim–Sulfamethoxazole for Uncomplicated Skin Infections
نویسندگان
چکیده
منابع مشابه
Clindamycin versus trimethoprim-sulfamethoxazole for uncomplicated skin infections.
BACKGROUND Skin and skin-structure infections are common in ambulatory settings. However, the efficacy of various antibiotic regimens in the era of community-acquired methicillin-resistant Staphylococcus aureus (MRSA) is unclear. METHODS We enrolled outpatients with uncomplicated skin infections who had cellulitis, abscesses larger than 5 cm in diameter (smaller for younger children), or both...
متن کاملMoxifloxacin versus Levofloxacin for Uncomplicated Skin and Skin Structure Infections: Treatment Durations, Failures, and Charges
• Objective: The approved therapy durations for the once-daily fluoroquinolones moxifloxacin and levofloxacin are 7 days and 7 to 10 days, respectively. We studied whether these labeling differences translated into differences in treatment duration, failure rates, or treatment charges in the treatment of uncomplicated skin and structure infections. • Design: Retrospective database study of insu...
متن کاملCefoperazone versus clindamycin plus gentamicin for obstetric and gynecologic infections.
Cefoperazone was compared with clindamycin plus gentamicin for the treatment of pelvic infections. Of 102 women, 95 (93%) demonstrated a good clinical response (47 with cefoperazone and 48 with clindamycin plus gentamicin). Of the seven failures, four were secondary to side effects and three were clinical failures.
متن کاملTrimethoprim-Sulfamethoxazole versus Placebo for Uncomplicated Skin Abscess.
BACKGROUND U.S. emergency department visits for cutaneous abscess have increased with the emergence of methicillin-resistant Staphylococcus aureus (MRSA). The role of antibiotics for patients with a drained abscess is unclear. METHODS We conducted a randomized trial at five U.S. emergency departments to determine whether trimethoprim-sulfamethoxazole (at doses of 320 mg and 1600 mg, respectiv...
متن کاملVancomycin Combined With Clindamycin for the Treatment of Acute Bacterial Skin and Skin-Structure Infections.
BACKGROUND Acute bacterial skin and skin-structure infections (ABSSSIs) are common causes of hospital admissions. These infections are often caused by methicillin-resistant Staphylococcus aureus; therefore, vancomycin remains a commonly used therapy. The purpose of this study was to compare hospital length of stay (LOS) in patients treated with vancomycin monotherapy vs combination therapy with...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: New England Journal of Medicine
سال: 2015
ISSN: 0028-4793,1533-4406
DOI: 10.1056/nejmoa1403789